Inflammation is one of the main reasons that cannabidiol (CBD) has become so well known. Of all its uses, inflammation is one of the most widely known and studied benefits of taking this compound. In a study from the Proceedings of the National Academy of Sciences of the United States of America (PNAS), it is explained why and how CBD impacted mice with arthritis.
Mice in this study had both collagen-induced arthritis (CIA) and type 2 collagen (CII) arthritis. CBD was given after mice had shown symptoms of arthritis, and after this treatment, CBD was shown to be an effective treatment both orally and intraperitoneally. The article states:
"CBD-treated mice showed a diminished CII-specific proliferation and IFN-γ production, as well as a decreased release of tumor necrosis factor by knee synovial cells. In vitro effects of CBD included a dose-dependent suppression of lymphocyte proliferation, both mitogen-stimulated and antigen-specific, and the blockade of the Zymosan-triggered reactive oxygen burst by peritoneal granulocytes."
It was also shown that CBD blocked the rise of lipopolysaccharide (a large molecule that provokes a strong immune response in animals). Because of these findings, it was concluded that CBD has a potent anti-arthritic effect in CIA, because of its immunosuppressive and anti-inflammatory properties.
It becomes obvious why CBD has become so well known for helping people with inflammation and arthritis. Here at That’s Natural, we believe that full-spectrum CBD oil is the best way to create a synergistic and healing effect. Our plants are grown with love by farmers using organic and biodynamic farming processes. It is then put through a Supercritical CO2 extraction process to ensure the purity of the product. We believe that you, the customer, should have confidence in your entire supply chain. We believe that you deserve products that are made with the intent to heal. This is why we strive to provide the most pure, potent, and trusted products available at That’s Natural!