Over 60,000 Americans are diagnosed with Parkinson’s Disease (PD) each year, while approximately 10,000,000 people worldwide live with the effects of this disease. PD is caused by a loss of brain cells in the substantia nigra, the part of the brain that produces dopamine (a chemical messenger). So, it is no surprise that Cannabidiol (CBD) has been shown to help those with PD find some relief from the symptoms.
This study showed that while there were no adverse effects, and no worsening of motor function, it did decrease the total scores of the Unified Parkinson’s Disease Rating Scale (UPDRS). They claim that:
No adverse effect was observed during the treatment. These preliminary data suggest that CBD may be effective, safe and well tolerated for the treatment of the psychosis in PD.
Another study showed that even though their 119 patients didn’t see any statistically significant difference in UPDRS scores while given CBD, scores on the Parkinson’s Disease Questionaire – 39 test were significantly different than those given a placebo. Their conclusion was as follows:
"Our findings point to a possible effect of CBD in improving quality of life measures in PD patients with no psychiatric comorbidities; however, studies with larger samples and specific objectives are required before definitive conclusions can be drawn."
A third study from the Movement Disorder Society showed that CBD may be useful in the treatment of motor complications in PD. In this study, it was shown that the long-term impacts of levodopa were not nearly as severe with CBD as without it.
Although more research is likely needed, there is strong evidence to support the premise that CBD does help alleviate some of the symptoms that are most bothersome to those with PD.
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